Galanthus nivalis lectin, unlike most mannose-specific lectins,
is not a metalloprotein and does not require Ca++ or Mn++ for binding.
Binding seems to be preferentially directed toward structures
containing (α-1,3) mannose residues. Also in contrast to most
mannose-binding lectins, GNL will not bind α-linked glucose.
Reports indicate that this lectin binds rat and mouse IgM but
not IgG. The only protein from human serum reported to bind
to this lectin is α2-macroglobulin. GNL binds to many viral
Inhibiting/Eluting Sugar: 100 mM - 200 mM α-methylmannoside