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Hippeastrum Hybrid Lectin (HHL, AL) |
This lectin is composed of four subunits of identical size and
is immunologically related to GNL and NPL. Amaryllis lectin
binds only α-mannose residues, unlike Con A, LCA and PSA
that also bind α-glucosyl structures. Like NPL there appears to
be an extended binding site for polymannose structures, not
requiring mannose to be at the non-reducing terminus. HHL
binds both (α-1,3) and (α-1,6) linked mannose structures, as
well as some yeast galactomannans.
Inhibiting Sugar: 100 mM α-methylmannoside
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