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Featuring:
Plus
quality reagents for:
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Lycopersicon Esculentum (Tomato) Lectin (LEL, TL) |
Tomato lectin is a very stable single subunit glycoprotein
containing about 50 percent arabinose and galactose and
may form multimeric aggregates in solution. Tomato lectin,
although sharing some specificities with potato lectin, Datura
lectin, and wheat germ agglutinin, has been reported to be
dissimilar in many respects. LEL binds well to glycophorin and
Tamm-Horsfall glycoprotein and has been used effectively to
label vascular endothelium in rodents.
Tomato lectin (from Lycopersicon esculentum) is an effective marker of blood vessels and microglial cells in rodents. Conjugation of the lectin with a fluorophore facilitates fast, one-step detection and visualization using intravascular perfusion methods or direct application to tissue sections.
Texas Red® or DyLight 594® conjugated tomato lectin provides an excellent contrast to green/yellow fluorescence such as GFP expressed in transgenic animals, or with fluorescein conjugates in standard double label studies. The tomato lectin complements our existing range of lectin reagents and should be a valuable tool in examining rodent tumor angiogenesis, tracing neovascular development in xenograft models and brain research.
Inhibiting/Eluting Sugar: Chitin Hydrolysate
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Frozen section of colon viewed under fluorescein filter: Lycopersicon esculentum lectin (orange staining with Vector® Red) and glandular epithelium (green fluorescein label)
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