Pisum sativum agglutinin is nearly identical in structure and
carbohydrate specificity to Lens culinaris agglutinin. The
lectin has specificity toward α-linked mannose-containing
oligosaccharides, with an N-acetylchitobiose-linked α-fucose
residue included in the receptor sequence. Calcium and
manganese ions are required for activity. PSA has been used to
fractionate cells, to isolate glycoproteins and glycopeptides, to
distinguish between normal and virally transformed cells, as a
T-cell mitogen, and as an inhibitor of allograft rejection.
Inhibiting/Eluting Sugar: mixture of 200 mM α-methylmannoside/200
mM α-methylglucoside
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