| About Vector
When Vector Laboratories was founded more than 30
years ago, monoclonal antibodies, biotin-avidin products
or lines of lectins were not available in the marketplace.
In 1976, we purified the first line of lectins and
quickly became the world’s leading supplier
of these products for use in studying glycoconjugates
in tissues, on cells, or isolated from fluids or extracts.
In our second year we introduced the Biotin-Avidin
System. Realizing that the strong interaction between
biotin and avidin could be utilized to form nearly
covalent linkages between a molecule derivatized with
biotin and avidin conjugated with a detectable label,
we provided the research community with the first
set of Biotin-Avidin System reagents. These first
products, consisting of biotinylated proteins and
avidin conjugates, began a revolution in detection
methods. Our biotinylated anti-mouse immunoglobulin
and labeled avidin proved to be the most widely used
reagents for detecting and characterizing monoclonal
antibodies. After several years, other companies recognized
their importance and began offering their own versions
of these products. More than twenty years ago, we
developed and patented processes that enabled complexes
between avidin or streptavidin and biotinylated enzymes,
designated ABC’s, to be formed. This achievement
established the basis for the VECTASTAIN®ABC family
of products. While other detection systems produced
faint or diffuse staining in tissue sections and required
high concentrations of primary antibodies, the VECTASTAIN®ABC
system gave dark, discrete, background-free staining
with extremely low concentrations of primary antibodies.
Improvements over the years led to the VECTASTAIN®Elite
ABC - widely recognized today as the most sensitive,
reliable and economical peroxidase-based staining
system available. After several years of development
we introduced the ImmPRESS™ reagents. These
new reagents are not based on biotin/avidin technology
but rely on a novel method of polymerizing peroxidase
and attach the high-density peroxidase "micropolymers"
directly to secondary antibodies.
Expanding on our expertise in non-radioisotopic detection
methods, we have developed new and improved ways of
labeling nucleic acid probes. PHOTOPROBE®Biotin
is used to randomly label any nucleic acid with biotin.
The FastTag®labeling system allows nucleic acid
to be easily and economically labeled with any marker.
The 3’ EndTag™ and 5’ EndTag™
system provide simple methods to label only the ends
of nucleic acid probes.
Remaining focused on our goal of providing the most
innovative detection systems, over the years we have
introduced fusion protein isolation systems, novel
enzyme substrates, neuronal tracers, mounting media,
streptavidin products, lectins with unique specificities,
many ultrapure immunological reagents, and a variety
of compounds for labeling, isolating and detecting
proteins, carbohydrates and nucleic acids. We also
continue to offer a series of important monoclonal
antibodies for immunohistochemcial applications.
Vector Laboratories’ major objectives have
always been to produce only reagents of the highest
quality, to have an accessible technical staff to
ensure prompt and personal assistance in the use of
these reagents, and to develop products which would
provide significant advances over current technologies.
We never compromise our high standards of product
purity and performance for the sake of expediency.
Every item in our catalog is produced with a strong
emphasis on quality control to ensure a consistently
reliable product. If any change in a product is made,
it is only to improve its performance.
Each of our products is accompanied by a specification
sheet which includes analytical data on the specific
lot and other pertinent information. Current references
and information concerning the most recent applications
for our reagents are available. We have included a
business reply card in the back of the catalog which
you may complete and return to us if you would like
to receive additional information regarding a specific
topic. Much of the technical information for our products,
including material safety data sheets (MSDS), is available
on our website.
Vector Laboratories is not only committed to producing
reagents for your present needs but also recognizes
that the development of new products is necessary
for continued success. The products included in this
catalog reflect that commitment. We hope to satisfy
the needs you may have tomorrow with the reagents
we are developing today. Through a combination of
our diligence and your scrutiny, our products will
remain unmatched in quality and performance and continue
to be the standards by which others are measured.
Trademarks of Vector: ABC-AmP, Animal-Free Blocker, AT-Yellow, DuoLuX, Elite, EndTag, FastTag,
Fusion Aid, GC-Red, HYBEX, ImmEdge, ImmPACT, ImmPRESS, ImmPrint, M.O.M., NEUROBIOTIN, NicKit p.s.o., PHOTOPROBE, PolyBlock, ProFusion, ProtOn, Quant*Tag, Resolve-It, UltraSNAP, VECTABOND, VectaMount, VECTASHIELD, VECTASHIELD HardSet, VECTASTAIN,
Vector, Vector Black, Vector Blue, Vector NovaRED, Vector Red, VECTREX.
Others: ABTS-Boehringer Mannheim; Texas Red-Molecular
Probes, TSA-NEN Life Sciences Products; APS-5 Lumigen
Inc. DuoLuX is a special formula of APS-5 produced for Vector Labs by Lumigen Inc. Southfield, MI.